Journal: Cancer Management and Research
Article Title: Identification of Urinary Exosomal miRNAs for the Non-Invasive Diagnosis of Prostate Cancer
doi: 10.2147/CMAR.S272140
Figure Lengend Snippet: Expression of 5 candidate exosomal miRNAs in the urine samples of the validation cohort. Relative expression levels of urinary exosomal miR-375 ( A ), miR-16-2-3p ( B ), miR-486-3p ( C ), miR-451a ( D ), and miR-486-5p ( E ) in patients with PCa. Data presented as relative fold changes.
Article Snippet: A genome-wide expression profiling of exosomal miRNAs obtained by Illumina NGS technology showed that urine from PCa patients had 39 down-regulated miRNAs and 14 up-regulated miRNAs compared with urine from the healthy controls , and urine from metastatic PCa patients had 7 down-regulated miRNAs compared with the urine of localized PCa patients ( ).
Techniques: Expressing, Biomarker Discovery